Primidone

Evidence-based neurology checklist on primidone: Mode of action The mode of action of Primidone is unknown Indications Dosing Interactions with other AEDs Neuropsychiatric side effects Genitourinary side effects Systemic side effects

Mode of action

  • The mode of action of Primidone is unknown

Indications

Dosing

Interactions with other AEDs

Neuropsychiatric side effects

Genitourinary side effects

Systemic side effects

References

  1. Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415. 
  2. Michelucci R, Pasini E, Riguzzi P, Andermann E, Kälviäinen R, Genton P. Myoclonus and seizures in progressive myoclonus epilepsies: pharmacology and therapeutic trials. Epileptic Disord 2016; 18:145-153.
  3. Johannessen SI, Landmark CJ. Antiepileptic drug interactions - principles and clinical implications. Curr Neuropharmacol 2010; 8:254-267.
  4. Benetello P, Furlanut M. Primidone-carbamazepine interaction: clinical consequences. Int J Clin Pharmacol Res 1987; 7:165-168.
  5. Kanner AM, Parra J, Frey M. The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicity. Epilepsia 2000; 41:1310-1314.
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