Investigational anti-seizure medications (ASMs)

Evidence-based neurology checklist on investigational anti-seizure medications (asms): Neurosteroids Allopregnanolone Ganaxolone SAGE-217 SAGE-547 Other investigational AEDs

Neurosteroids

  • Allopregnanolone
  • Ganaxolone
  • SAGE-217
  • SAGE-547

Other investigational AEDs

References

  1. Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII). Epilepsia 2017; 58:181-221.
  2. Mula M. Investigational new drugs for focal epilepsy. Expert Opin Investig Drugs 2016; 25:1-5. 
  3. Mudigoudar B, Weatherspoon S, Wheless JW. Emerging antiepileptic drugs for severe pediatric epilepsies. Semin Pediatr Neurol 2016; 23:167-179. 
  4. Khalil A, Kovac S, Morris G, Walker MC. Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline. Epilepsia 2017; 58:263-273.
  5. Sperling MR, Klein P, Tsai J. Randomized, double-blind, placebo-controlled phase 2 study of ganaxolone as add-on therapy in adults with uncontrolled partial-onset seizures. Epilepsia 2017; 58:558-564.
  6. And 4 more. Subscribe to see the full list

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