Multiple sclerosis (MS): classification

Evidence-based neurology checklist on multiple sclerosis (ms): classification: Relapsing remitting MS (RRMS) Repeated demyelinating attacks affecting different CNS areas lasting >24 hours or One demyelinating attack with MRI or CSF features of dissemination in time and place Primary progressive MS…

Relapsing remitting MS (RRMS)

  • Repeated demyelinating attacks affecting different CNS areas lasting >24 hours or
  • One demyelinating attack with MRI or CSF features of dissemination in time and place

Primary progressive MS (PPMS)

Secondary progressive MS (SPMS)

Benign (non-progressive) MS

Spinal onset MS

Pure spinal MS

Myelocortical MS

Cortically dominant MS

Oligoclonal band (OCB) negative MS

Marburg variant

Schilder’s disease (myelinoclastic diffuse sclerosis)

Other forms and variants of MS

References

  1. Selchen D, Bhan V, Blevins G, et al. MS, MRI, and the 2010 McDonald criteria: A Canadian expert commentary. Neurology 2012; 79:S1-S15.
  2. Zeydan B, Gu X, Atkinson EJ, et al. Cervical spinal cord atrophy: an early marker of progressive MS onset. Neurol Neuroimmunol Neuroinflamm 2018; 5:e435. 
  3. Skoog B, Runmarker B, Winblad S, Ekholm S, Andersen O. A representative cohort of patients with non-progressive multiple sclerosis at the age of normal life expectancy. Brain 2012; 135:900-911.
  4. Skoog B, Runmarker B, Winbald S, Ekholm S, Andersen O. A representative cohort of patients with non-progressive multiple sclerosis at the age of normal life expectancy. Brain 2012; 135:900-911.
  5. Gajofatto A, Turatti M, Bianchi MR, et al. Benign multiple sclerosis: physical and cognitive impairment follow distinct evolutions. Acta Neurol Scand 2016; 133:183-191. 
  6. And 16 more. Subscribe to see the full list

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