Viral encephalitis: relapse

Evidence-based neurology checklist on viral encephalitis: relapse: Demographic features Relapses occur in 14-26% of people with HSV encephalitis This usually affects children It occurs within weeks of the infection Pathogenesis Clinical features

Demographic features

  • Relapses occur in 14-26% of people with HSV encephalitis
  • This usually affects children
  • It occurs within weeks of the infection

Pathogenesis

Clinical features

References

  1. Titulaer MJ, Leypoldt F, Dalmau J. Antibodies to N-methyl-D-aspartate and other synaptic receptors in choreoathetosis and relapsing symptoms post-herpes virus encephalitis. Mov Disord 2014; 29:3-6.
  2. De Tiège X, Rozenberg F, Des Portes V, et al. Herpes simplex encephalitis relapses in children: differentiation of two neurologic entities. Neurology 2003; 61:241-243.
  3. Lim HK, Seppänen M, Hautala T, et al. TLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk. Neurology 2014; 83:1888-1897.
  4. Zhang SY, Jouanguy E, Ugolini S, et al. TLR3 deficiency in patients with herpes simplex encephalitis. Science 2007; 317:1522-1527.
  5. Guo Y, Audry M, Ciancanelli M, et al. Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity. J Exp Med 2011; 208:2083-2098.

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