Viral encephalitis: prognostic features
Evidence-based neurology checklist on viral encephalitis: prognostic features: Poor prognostic features Older age Reduced consciousness or coma at treatment onset Restricted diffusion on brain magnetic resonance imaging (MRI) Delay in commencing Acyclovir Not using corticosteroids…
Poor prognostic features
- Older age
- Reduced consciousness or coma at treatment onset
- Restricted diffusion on brain magnetic resonance imaging (MRI)
- Delay in commencing Acyclovir
- Not using corticosteroids
- Thrombocytopaenia
- Cerebral oedema
Features with no prognostic implications
References
- Kamei S, Sekizawa T, Shiota H, et al. Evaluation of combination therapy using aciclovir and corticosteroid in adult patients with herpes simplex virus encephalitis. JNNP 2005; 76:1544-1549.
- Singh TD, Fugate JE, Hocker S, Wijdicks EF, Aksamit AJ Jr, Rabinstein AA. Predictors of outcome in HSV encephalitis. J Neurol 2016; 263:277-289.
- Thakur KT, Motta M, Asemota AO, et al. Predictors of outcome in acute encephalitis. Neurology 2013; 81:793–800.
