Hereditary spastic paraplegia type 41 (SPG41)

Evidence-based neurology checklist on hereditary spastic paraplegia type 41 (spg41): Genetics This is caused by mutations in chromosome 11p The transmission is autosomal dominant It usually presents as pure HSP The mean onset age is about 16 years Clinical features

Genetics

  • This is caused by mutations in chromosome 11p
  • The transmission is autosomal dominant
  • It usually presents as pure HSP
  • The mean onset age is about 16 years

Clinical features

References

  1. Zhao GH, Hu ZM, Shen L, et al. A novel candidate locus on chromosome 11p14.1-p11.2 for autosomal dominant hereditary spastic paraplegia. Chin Med J (Engl) 2008; 121:430-434. 

Related checklists

Loading...