Hereditary spastic paraplegia type 38 (SPG38)

Evidence-based neurology checklist on hereditary spastic paraplegia type 38 (spg38): Genetics This is caused by mutations in chromosome 4p The transmission is autosomal dominant It is allelic with SPG4 It is similar to Silver syndrome Clinical features

Genetics

  • This is caused by mutations in chromosome 4p
  • The transmission is autosomal dominant
  • It is allelic with SPG4
  • It is similar to Silver syndrome

Clinical features

References

  1. Orlacchio A, Patrono C, Gaudiello F, et al. Silver syndrome variant of hereditary spastic paraplegia: A locus to 4p and allelism with SPG4. Neurology 2008; 70:1959-1966. 

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