Hereditary spastic paraplegia type 36 (SPG36)

Evidence-based neurology checklist on hereditary spastic paraplegia type 36 (spg36): Genetics This is caused by mutations in chromosome 12q The transmission is autosomal dominant The mean onset age is 24 years Clinical features Magnetic resonance imaging (MRI) brain

Genetics

  • This is caused by mutations in chromosome 12q
  • The transmission is autosomal dominant
  • The mean onset age is 24 years

Clinical features

Magnetic resonance imaging (MRI) brain

References

  1. Schüle R, Bonin M, Dürr A, et al. Autosomal dominant spastic paraplegia with peripheral neuropathy maps to chr12q23-24. Neurology 2009; 72:1893-1898. 

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