Autoimmune encephalitis: investigations
Evidence-based neurology checklist on autoimmune encephalitis: investigations: Main investigations Magnetic resonance imaging (MRI) brain Positron emission tomography (PET) scan brain: if MRI is normal Electroencephalogram (EEG) Cerebrospinal fluid (CSF) analysis Brain biopsy Paraneoplastic screen…
Main investigations
- Magnetic resonance imaging (MRI) brain
- Positron emission tomography (PET) scan brain: if MRI is normal
- Electroencephalogram (EEG)
- Cerebrospinal fluid (CSF) analysis
- Brain biopsy
Paraneoplastic screen
Autoantibody tests
Other tests
References
- Abboud H, Probasco JC, Irani S, et al. Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management. JNNP 2021; 92:757-768.
- Abboud H, Probasco J, Irani SR, et al. Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management. JNNP 2021; 92:897-907.
- Konen FF, Bucak E, Bachhuber F, et al. Kappa free light chain for diagnosis and neurofilament light chain for prognosis in autoimmune encephalitis. Neurol Neuroimmunol Neuroinflamm 2026; 13:e200630.
