PARK5 genetic Parkinson's disease (PD)

Evidence-based neurology checklist on park5 genetic parkinson's disease (pd): Genetics This is possibly caused by mutations in the UCHL1 gene on chromosome 4p The transmission is autosomal dominant Only one family has been reported Clinical features Treatment

Genetics

  • This is possibly caused by mutations in the UCHL1 gene on chromosome 4p
  • The transmission is autosomal dominant
  • Only one family has been reported

Clinical features

Treatment

References

  1. Leroy E, Boyer R, Auburger G, et al. The ubiquitin pathway in Parkinson's disease. Nature 1998; 395:451-452.
  2. Healy DG, Abou-Sleiman PM, Casas JP, et al. UCHL-1 is not a Parkinson's disease susceptibility gene. Ann Neurol 2006; 59:627-633.

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