HIV associated myelopathies

Evidence-based neurology checklist on hiv associated myelopathies: HIV associated vacuolar myelopathy (HAM) This starts in the mid to low thoracic spinal cord It progresses rostrally with increasing severity It presents with painless spastic paraparesis It also manifests with sensory ataxia There…

HIV associated vacuolar myelopathy (HAM)

  • This starts in the mid to low thoracic spinal cord
  • It progresses rostrally with increasing severity
  • It presents with painless spastic paraparesis
  • It also manifests with sensory ataxia
  • There is associated neurogenic bladder
  • The magnetic resonance imaging (MRI) shows spinal cord atrophy
  • The MRI may also show an intrinsic cord signal

HIV associated myelitis

References

  1. McArthur JC, Brew BJ, Nath A. Neurological complications of HIV infection. Lancet Neurol 2005; 4:543-555.
  2. Tan SV, Guiloff RJ, Scaravilli F. AIDS-associated vacuolar myelopathy: a morphometric study. Brain 1995; 118:1247-1261.
  3. Chong J, Di Rocco A, Tagliati M, Danisi F, Simpson DM, Atlas SW. MR findings in AIDS-associated myelopathy. Am J Neuroradiol 1999; 20:1412-1416.
  4. Andrade P, Figueiredo C, Carvalho C, Santos L, Sarmento A. Transverse myelitis and acute HIV infection: a case report. BMC Infect Dis 2014; 14:149.
  5. Hamada Y, Watanabe K, Aoki T, Arai N, Honda M, Kikuchi Y, Oka S. Primary HIV infection with acute transverse myelitis. Intern Med 2011; 50:1615-1617.

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