Heroin toxicity

Evidence-based neurology checklist on heroin toxicity: Modes of heroin delivery Inhalation of pyrolysate vapour Inhalation in water Intravenous injection Transconjunctival Central neurological presentations Peripheral neurological presentations Systemic presentations

Modes of heroin delivery

  • Inhalation of pyrolysate vapour
  • Inhalation in water
  • Intravenous injection
  • Transconjunctival

Central neurological presentations

Peripheral neurological presentations

Systemic presentations

References

  1. Tormoehlen LM. Toxic leukoencephalopathies. Psychiatr Clin North Am 2013; 36:277-292.
  2. Tormoehlen LM. Toxic leukoencephalopathies. Neurol Clin 2011; 29:591-605.
  3. Bach AG, Jordan B, Wegener NA, et al. Heroin spongiform leukoencephalopathy (HSLE). Clin Neuroradiol 2012; 22:345-349. 
  4. Kriegstein AR, Shungu DC, Millar WS, et al. Leukoencephalopathy and raised brain lactate from heroin vapor inhalation ("chasing the dragon"). Neurology 1999; 53:1765-1773.
  5. Alambyan V, Pace J, Miller B, et al. The emerging role of inhaled heroin in the opioid epidemic: a review. JAMA Neurol 2018; 75:1423-1434.
  6. And 22 more. Subscribe to see the full list

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