Stroke treatment with atrial fibrillation (AF)

Evidence-based neurology checklist on stroke treatment with atrial fibrillation (af): Treatment options for first time stroke Anticoagulation is preferred over antiplatelets Non-vitamin K antagonist oral anticoagulants are preferred Timing of anticoagulation Treatment of recurrent stroke whilst on…

Treatment options for first time stroke

  • Anticoagulation is preferred over antiplatelets
  • Non-vitamin K antagonist oral anticoagulants are preferred

Timing of anticoagulation

Treatment of recurrent stroke whilst on anticoagulation

Precautions when treating recurrent stroke whilst on anticoagulation

Acronym

References

  1. Klijn CJM, Paciaroni M, Berge E, et al. Antithrombotic treatment for secondary prevention of stroke and other thromboembolic events in patients with stroke or transient ischemic attack and non-valvular atrial fibrillation: A European Stroke Organisation guideline. Eur Stroke J 2019; doi.org/10.1177/2396987319841187. (Epub ahead of print).
  2. Lyon J, Nash PS, Ahmed N, et al. Early versus delayed anticoagulation in acute ischemic stroke according to atrial fibrillation subtype and time of diagnosis: subgroup analysis of the OPTIMAS randomized controlled trial. Stroke 2026; 57:1513-1525.
  3. Nash PS, Best JG, Lyon J, et al. Early versus delayed anticoagulation in acute ischemic stroke with atrial fibrillation according to infarct volume and location: a prespecified subgroup analysis of the OPTIMAS randomized controlled trial. Int J Stroke 2026 (Online ahead of print).
  4. Fasth O, Oldgren J, Ghukasyan Lakic T, et al. Early versus delayed DOAC after ischaemic stroke in atrial fibrillation: 1-year outcomes in the TIMING study and in concurrent practice. Eur Stroke J 2026; 11(2):aakag010. 
  5. Stretz C, Wu TY, Wilson D, Seiffge DJ, Smith EE, Gurol ME, Yaghi S. Ischaemic stroke in anticoagulated patients with atrial fibrillation. JNNP 2021; 92:1164-1172.
  6. And 3 more. Subscribe to see the full list

Related checklists

Loading...