Ischaemic stroke: investigational treatments
Evidence-based neurology checklist on ischaemic stroke: investigational treatments: Investigational stroke treatments Minocycline: it is potentially neuroprotective Peroxisome proliferator-activated receptor gamma agonists Glibenclamide Staphylokinase Tirofiban Recombinant human prourokinase…
Investigational stroke treatments
- Minocycline: it is potentially neuroprotective
- Peroxisome proliferator-activated receptor gamma agonists
- Glibenclamide
- Staphylokinase
- Tirofiban
- Recombinant human prourokinase
- Sublingual Edaravone dexborneol
- Minocycline
References
- Malhotra K, Chang JJ, Khunger A, et al. Minocycline for acute stroke treatment: a systematic review and meta-analysis of randomized clinical trials. J Neurol 2018; 265:1871-1879.
- Liu J, Wang LN. Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack. Cochrane Database Syst Rev 2014; 1:CD010693.
- Huang K, Hu Y, Wu Y, et al. Exploratory analysis of oral glibenclamide in acute ischemic stroke. Acta Neurol Scand 2019; 140:212-218.
- Gusev EI, Martynov MY, Nikonov AA, et al. Non-immunogenic recombinant staphylokinase versus alteplase for patients with acute ischaemic stroke 4·5 h after symptom onset in Russia (FRIDA): a randomised, open label, multicentre, parallel-group, non-inferiority trial. Lancet Neurol 2021; 20:721-728.
- Zi W, Song J, Kong W, et al. Tirofiban for stroke without large or medium-sized vessel occlusion. N Engl J Med 2023; 388:2025-2036.
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