Spastic paraparesis: investigations

Evidence-based neurology checklist on spastic paraparesis: investigations: Biochemistry tests Vitamin B12 Vitamin E Very long chain fatty acids (VLCFA) White cell enzymes Plasma amino acids Lipoproteins Copper and ceruloplasmin Microbiology Genetics Neurophysiology Other tests

Biochemistry tests

  • Vitamin B12
  • Vitamin E
  • Very long chain fatty acids (VLCFA)
  • White cell enzymes
  • Plasma amino acids
  • Lipoproteins
  • Copper and ceruloplasmin

Microbiology

Genetics

Neurophysiology

Other tests

References

  1. Salinas S, Proukakis C, Crosby A, Warner TT. Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms. Lancet Neurol 2008; 7:1127-1138.
  2. Warner T. Hereditary spastic paraplegia. ACNR 2007; 6: 16-17.
  3. Bargiela D, Eglon G, Horvath R, Chinnery PF. An under-recognised cause of spastic paraparesis in middle-aged women. Pract Neurol 2014; 14:182-184.

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