Radiologically isolated syndrome (RIS): predictors of conversion to MS

Evidence-based neurology checklist on radiologically isolated syndrome (ris): predictors of conversion to ms: Clinical Younger age Pregnancy Abnormal visual evoked potentials (VEPs) Kapa free light chain index Radiological Cerebrospinal fluid (CSF) Predictors of progression to primary progressive…

Clinical

  • Younger age
  • Pregnancy
  • Abnormal visual evoked potentials (VEPs)
  • Kapa free light chain index

Radiological

Cerebrospinal fluid (CSF)

Predictors of progression to primary progressive MS (PPMS)

RIS conversion and progression rate to MS

Acronyms

References

  1. Granberg T, Martola J, Kristoffersen-Wiberg M, Aspelin P, Fredikson S. Radiologically isolated syndrome-incidental magnetic resonance imaging findings suggestive of multiple sclerosis, a systematic review. Mult Scler 2013; 19:271-280.
  2. Siva A, Saip S, Altintas A, Jacob A, Kergan BM, Kantarci OH. Multiple sclerosis risk in radiologically uncovered asymptomatic possible inflammatory-demyelinating disease. Mult Scler 2009; 15:918-927.
  3. Lebrun C, LePage E, Kantarci O, et al. Impact of pregnancy on conversion to clinically isolated syndrome in a radiologically isolated syndrome cohort. Mult Scler 2012; 18:1297-1302.
  4. Levraut M, Gavoille A, Landes-Chateau C, et al. Kappa free light chain index predicts disease course in clinically and radiologically isolated syndromes. Neurol Neuroimmunol Neuroinflamm 2023; 10:e200156.
  5. Miller DH, Chard DT, Ciccarelli O. Clinically isolated syndromes. Lancet Neurol 2012; 11:157-169.
  6. And 7 more. Subscribe to see the full list

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