Primary progressive aphasia (PPA): non-fluent variant (nfvPPA)

Evidence-based neurology checklist on primary progressive aphasia (ppa): non-fluent variant (nfvppa): Diagnostic criteria Language impairment Cognitive features Behavioural and psychiatric features Motor disturbances Language features: manifestations Language features: relevance Cognitive features…

Diagnostic criteria

  • Language impairment
  • Cognitive features
  • Behavioural and psychiatric features
  • Motor disturbances

Language features: manifestations

Language features: relevance

Cognitive features

Behavioural and psychiatric features

Motor impairment

Dysphagia: clinical predictors

Dysphagia: radiological predictors: grey matter atrophy sites

Progression to other syndromes

Synonym

References

  1. Mesulem MM. Primary progressive aphasia. Ann Neurol 2001; 49: 425-432.
  2. Léger GC, Johnson N. A review on primary progressive aphasia. Neuropsychiatr Dis Treat 2007: 3:745–752.
  3. Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology 2011; 76:1006-1014.
  4. Rabinovici GD, Miller BL. Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs 2010; 24:375-398.
  5. Mulroy E, Core LB, Chokesuwattanaskul A, et al. Binary reversals: a diagnostic sign in primary progressive aphasia. JNNP 2023 (Online ahead of print).
  6. And 2 more. Subscribe to see the full list

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