Primary progressive aphasia (PPA): logopenic variant (lvPPA)
Evidence-based neurology checklist on primary progressive aphasia (ppa): logopenic variant (lvppa): Genetic mutations Progranulin (GRN) Microtubule-associated protein tau (MAPT) Pathological sites Clinical features Relatively spared speech functions Diagnostic criteria: core features Diagnostic…
Genetic mutations
- Progranulin (GRN)
- Microtubule-associated protein tau (MAPT)
Pathological sites
Clinical features
Relatively spared speech functions
Diagnostic criteria: core features
Diagnostic criteria: supportive features
Differentiating features from other PPA variants
Other differentials
Synonym
References
- Henry ML, Gorno-Tempini ML. The logopenic variant of primary progressive aphasia. Curr Opin Neurol 2010; 23:633-637.
- Rabinovici GD, Miller BL. Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs 2010; 24:375-398.
- Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology 2011; 76:1006-1014.
- Seelar H, Rohrer JD, Pijnenburg AL, Fox NC, van Swieten JC. Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review. JNNP 2011; 82:476-486.
- Chare L, Hodges JR, Leyton CE, et al. New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications. JNNP 2014; 85:866–871.
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