Primary progressive aphasia (PPA): ALS subtype (PPA-ALS)

Evidence-based neurology checklist on primary progressive aphasia (ppa): als subtype (ppa-als): Subtypes Non-fluent variant PPA ALS (nfvPPA-ALS or nfvPA-MND) Semantic variant PPA MND (svPPA-ALS) or svPA-MND) Genetics Clinical features Magnetic resonance imaging (MRI) brain Pathology Synonym

Subtypes

  • Non-fluent variant PPA ALS (nfvPPA-ALS or nfvPA-MND)
  • Semantic variant PPA MND (svPPA-ALS) or svPA-MND)

Genetics

Clinical features

Magnetic resonance imaging (MRI) brain

Pathology

Synonym

References

  1. Tan RH, Guennewig B, Dobson-Stone C, et al. The underacknowledged PPA-ALS: a unique clinicopathologic subtype with strong heritability. Neurology 2019; 92:e1354-e1366.
  2. Vinceti G, Olney N, Mandelli ML, et al. Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates. Amyotroph Lateral Scler Frontotemporal Degener 2019; 20:146-158. 

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