Posterior cortical atrophy (PCA)

Evidence-based neurology checklist on posterior cortical atrophy (pca): Patient profile This is a neurodegenerative disease predominantly involving the occipital and parietal cortex It is usually associated with Alzheimer’s disease (AD) The onset age is in the 50’s and early 60’s Women are…

Patient profile

  • This is a neurodegenerative disease predominantly involving the occipital and parietal cortex
  • It is usually associated with Alzheimer’s disease (AD)
  • The onset age is in the 50’s and early 60’s
  • Women are affected twice as often as men

Functional visual difficulties

Visual features

Cognitive features

Associated cortical syndromes

Systemic symptoms

Types of pathology

Investigations

Treatment

Synonym

References

  1. Husain M. Components of posterior cortical atrophy. JNNP 2012; 83:855.
  2. McMonagle P, Deering F, Berliner Y, Kertesz A. The cognitive profile of posterior cortical atrophy. Neurology 2006; 66:331-338.
  3. Tang-Wai DF, Graff-Radford NR, Boeve BF, et al. Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy. Neurology 2004; 63:1168-1174.
  4. Crutch SJ, Lehmann M, Schott JM, Rabinovici GD, Rossor MN, Fox NC. Posterior cortical atrophy. Lancet Neurol 2012; 11:170-178.
  5. Zakzanis VK, Boulos MI. Posterior cortical atrophy. Neurologist 2001; 7:341–349. 
  6. And 7 more. Subscribe to see the full list

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