Alzheimer’s disease (AD): variants classification

Evidence-based neurology checklist on alzheimer’s disease (ad): variants classification: Logopenic aphasia This AD variant is characterised by slow hesitant speech There are frequent and prolonged word-finding pauses Repetition performance is poor There is anomia Progressive dysexecutive syndrome…

Logopenic aphasia

  • This AD variant is characterised by slow hesitant speech
  • There are frequent and prolonged word-finding pauses
  • Repetition performance is poor
  • There is anomia

Progressive dysexecutive syndrome

Frontal or behavioural variant Alzheimer’s disease (FvAD)

Other variants

References

  1. Grecius MD, Geschwind MD, Miller BL. Presenile dementia syndromes: an update on taxonomy and diagnosis. JNNP 2002; 72:691-700.
  2. Rossor MN, Fox NC, Mummery CJ, Schott JN, Warren JD. The diagnosis of young-onset dementia. Lancet Neurol 2010; 9:793-806.
  3. Rabinovici GD, Miller BL. Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs 2010; 24:375-398. 
  4. Villain N, Dubois B. Alzheimer's disease including focal presentations. Semin Neurol 2019; 39:213-226.
  5. Townley RA, Graff-Radford J, Mantyh WG, et al. Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes. Brain Commun 2020; 2:fcaa068.
  6. And 14 more. Subscribe to see the full list

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