Post thymectomy myasthenia gravis (PTMG)

Evidence-based neurology checklist on post thymectomy myasthenia gravis (ptmg): Epidemiology Myasthenia gravis develops post thymectomy for thymoma in 4-2-8% of cases It develops between 18 days and 108 months post-operatively Risk factors Prevention

Epidemiology

  • Myasthenia gravis develops post thymectomy for thymoma in 4-2-8% of cases
  • It develops between 18 days and 108 months post-operatively

Risk factors

Prevention

References

  1. Tang M, Shao Y, Dong J, et al. Risk factors for postoperative myasthenia gravis in patients with thymoma without myasthenia gravis: a systematic review and meta-analysis. Front Oncol 2023; 13:1061264. 
  2. Kim A, Choi SJ, Kang CH, et al. Risk factors for developing post-thymectomy myasthenia gravis in patients with thymoma. Muscle Nerve 2021; 63:531-537.
  3. Mineo TC, Tamburrini A, Schillaci O, Ambrogi V. Onset and evolution of clinically apparent myasthenia gravis after resection of non-myasthenic thymomas. Semin Thorac Cardiovasc Surg 2018; 30:222-227. 
  4. Nabe Y, Hashimoto T, Tanaka K, et al. Relationship between anti-acetylcholine receptor antibodies and the development of post-thymectomy myasthenia gravis in patients with thymoma: a single-center experience. Gland Surg 2021; 10:2408-2413.
  5. Yamada Y, Yoshida S, Iwata T, et al. Risk factors for developing postthymectomy myasthenia gravis in thymoma patients. Ann Thorac Surg 2015; 99:1013-1019. 
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