Myotonic dystrophy type 1 and cancer

Evidence-based neurology checklist on myotonic dystrophy type 1 and cancer: Risk factors for cancer Older age Earlier age at diagnosis of myotonic dystrophy Female gender: for benign tumours only Down-regulation of miRNA-200/141 The risk is not associated with lifestyle risk factors The risk is…

Risk factors for cancer

  • Older age 
  • Earlier age at diagnosis of myotonic dystrophy
  • Female gender: for benign tumours only
  • Down-regulation of miRNA-200/141
  • The risk is not associated with lifestyle risk factors
  • The risk is not familial
  • The risk is not related to CTG repeat expansion length

Most frequent reported cancers

Other reported cancers

References

  1. Wang Y, Pfeiffer RM, Alsaggaf R, et al. Risk of skin cancer among patients with myotonic dystrophy type 1 based on primary care physician data from the U.K. Clinical Practice Research Datalink. Int J Cancer 2017; 142:1174-1181.
  2. Win AK, Perattur PG, Pulido JS, Pulido CM, Lindor NM. Increased cancer risks in myotonic dystrophy. Mayo Clin Proc 2012; 87:130-135. 
  3. Mohamed S, Pruna L, Kaminsky P. Increasing risk of tumors in myotonic dystrophy type 1. Presse Med 2013; 42:e281-e284. 
  4. Bianchi ML, Leoncini E, Masciullo M, et al. Increased risk of tumor in DM1 is not related to exposure to common lifestyle risk factors. J Neurol 2016; 263:492-498. 
  5. Fernández-Torrón R, García-Puga M, Emparanza JI, et al. Cancer risk in DM1 is sex-related and linked to miRNA-200/141 downregulation. Neurology 2016; 87:1250-1257.
  6. And 11 more. Subscribe to see the full list

Related checklists

Loading...