Migraine: pathophysiological mechanisms
Evidence-based neurology checklist on migraine: pathophysiological mechanisms: Impaired neuropeptide activity Calcitonin gene receptor peptide (CGRP) Pituitary adenylate cyclase-activating polypeptide Substance P Neuropeptide Y Vasoactive intestinal peptide (VIP) Other pathophysiological risk…
Impaired neuropeptide activity
- Calcitonin gene receptor peptide (CGRP)
- Pituitary adenylate cyclase-activating polypeptide
- Substance P
- Neuropeptide Y
- Vasoactive intestinal peptide (VIP)
Other pathophysiological risk factors
References
- Scher AI, Terwindt GM, Verschuren WM, et al. Migraine and MTHFR C677T genotype in a population-based sample. Ann Neurol 2006; 59:372-375.
- Tajti J, Szok D, Majláth Z, Tuka B, Csáti A, Vécsei L. Migraine and neuropeptides. Neuropeptides 2015; 52:19-30.
- Karsan N, Goadsby PJ. Calcitonin gene-related peptide and migraine. Curr Opin Neurol 2015; 28:250-254.
- Bhaskar S, Saeidi K, Borhani P, Amiri H. Recent progress in migraine pathophysiology: role of cortical spreading depression and magnetic resonance imaging. Eur J Neurosci 2013; 38:3540-3551.
- Hamel E. Serotonin and migraine: biology and clinical implications. Cephalalgia 2007; 27:1293-1300.
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