Immune checkpoint inhibitors (ICI): pharmacology

Evidence-based neurology checklist on immune checkpoint inhibitors (ici): pharmacology: Pharmacology The immune checkpoint inhibitors are monoclonal antibodies They are directed against immune checkpoint receptors Classification Indications Toxicity Treatment of toxicity Acronyms

Pharmacology

  • The immune checkpoint inhibitors are monoclonal antibodies
  • They are directed against immune checkpoint receptors

Classification

Indications

Toxicity

Treatment of toxicity

Acronyms

References

  1. Hottinger AF. Neurologic complications of immune checkpoint inhibitors. Curr Opin Neurol 2016; 29:806-812.
  2. Izzedine H, Mateus C, Boutros C, et al. Renal effects of immune checkpoint inhibitors. Nephrol Dial Transplant 2017; 32:936-942.
  3. Karamchandani DM, Chetty R. Immune checkpoint inhibitor-induced gastrointestinal and hepatic injury: pathologists' perspective. J Clin Pathol 2018; 71:665-671.
  4. Simmons D, Lang E. The most recent oncologic emergency: what emergency physicians need to know about the potential complications of immune checkpoint inhibitors. Cureus 2017; 9:e1774.
  5. Sepúlveda M, Martinez-Hernandez E, Gaba L, et al. Motor polyradiculopathy during pembrolizumab treatment of metastatic melanoma. Muscle Nerve 2017; 56:E162-E167.
  6. And 11 more. Subscribe to see the full list

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