Hereditary spastic paraplegia type 71 (SPG71)

Evidence-based neurology checklist on hereditary spastic paraplegia type 71 (spg71): Genetics This is caused by mutations in the ZFR gene on chromosome 5p The transmission is autosomal recessive The onset age is 1 year Clinical features Magnetic resonance imaging (MRI) brain: features

Genetics

  • This is caused by mutations in the ZFR gene on chromosome 5p
  • The transmission is autosomal recessive
  • The onset age is 1 year

Clinical features

Magnetic resonance imaging (MRI) brain: features

References

  1. Novarino G, Fenstermaker AG, Zaki MS, et al. Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders. Science 2014; 343:506-511. 

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