Hereditary spastic paraplegia type 61 (SPG61)

Evidence-based neurology checklist on hereditary spastic paraplegia type 61 (spg61): Genetics This is caused by mutations in the ARL61P1 gene on chromosome 16p The transmission is autosomal recessive The onset age is 14 months Clinical features

Genetics

  • This is caused by mutations in the ARL61P1 gene on chromosome 16p
  • The transmission is autosomal recessive
  • The onset age is 14 months

Clinical features

References

  1. Novarino G, Fenstermaker AG, Zaki MS, et al. Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders. Science 2014; 343:506-511. 

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