Febrile infection-related epilepsy syndrome (FIRES)
Evidence-based neurology checklist on febrile infection-related epilepsy syndrome (fires): Pathology This is a post-infectious epileptic encephalopathy It is presumed to be autoimmune but the usual antibodies are negative The seizure focus is in the medial temporal lobe Onset features Clinical…
Pathology
- This is a post-infectious epileptic encephalopathy
- It is presumed to be autoimmune but the usual antibodies are negative
- The seizure focus is in the medial temporal lobe
Onset features
Clinical features
Associated features
Clinical phases
Magnetic resonance imaging (MRI)
Electroencephalogram (EEG)
Treatment
Investigational treatment
Synonyms
References
- van Baalen A, Häusler M, Plecko-Startinig B, et al. Febrile infection-related epilepsy syndrome without detectable autoantibodies and response to immunotherapy: a case series and discussion of epileptogenesis in FIRES. Neuropediatrics 2012; 43:209-216.
- Caputo D, Iorio R, Vigevano F, Fusco L. Febrile infection-related epilepsy syndrome (FIRES) with super-refractory status epilepticus revealing autoimmune encephalitis due to GABAAR antibodies. Eur J Paediatr Neurol 2018; 22:182-185.
- Serrano-Castro PJ, Quiroga-Subirana P, Payán-Ortiz M, Fernandez-Perez J. The expanding spectrum of febrile infection-related epilepsy syndrome (FIRES). Seizure 2013; 22:153-155.
- Caraballo RH, Reyes G, Avaria MF, et al. Febrile infection-related epilepsy syndrome: a study of 12 patients. Seizure 2013; 22:553-559.
- Nabbout R. Autoimmune and inflammatory epilepsies. Epilepsia 2012; 53(Suppl. 4):58–62.
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