Ecstasy (MDMA) toxicity

Evidence-based neurology checklist on ecstasy (mdma) toxicity: Chemistry This is 3,4-methylenedioxymethamphetamine It is derived from methamphetamine It is a hallucinogen It reduces brain serotonin levels Acute neuropsychiatric effects Acute cardiovascular effects Later effects Magnetic resonance…

Chemistry

  • This is 3,4-methylenedioxymethamphetamine
  • It is derived from methamphetamine
  • It is a hallucinogen
  • It reduces brain serotonin levels

Acute neuropsychiatric effects

Acute cardiovascular effects

Later effects

Magnetic resonance imaging (brain)

References

  1. Geibprasert S, Gallucci M, Krings T. Addictive illegal drugs: structural neuroimaging. AJNR Am J Neuroradiol 2010; 31:803-808.
  2. Sarkar S, Schmued L. Neurotoxicity of ecstasy (MDMA): an overview. Curr Pharm Biotechnol 2010; 11:460-469.
  3. Capela JP, Carmo H, Remião F, Bastos ML, Meisel A, Carvalho F. Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview. Mol Neurobiol 2009; 39:210-271.

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