Cannabis (marijuana) toxicity
Evidence-based neurology checklist on cannabis (marijuana) toxicity: Chemistry The active compound is δ-9-tetrahydrocannabinol It is taken by inhalation or orally Acute neurological features Acute cardiovascular features Acute systemic features Chronic neurological features Cannabis withdrawal…
Chemistry
- The active compound is δ-9-tetrahydrocannabinol
- It is taken by inhalation or orally
Acute neurological features
Acute cardiovascular features
Acute systemic features
Chronic neurological features
Cannabis withdrawal features
Magnetic resonance imaging (MRI) brain
References
- Geibprasert S, Gallucci M, Krings T. Addictive illegal drugs: structural neuroimaging. AJNR Am J Neuroradiol 2010; 31:803-808.
- Burggren AC, Shirazi A, Ginder N, London ED. Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives. Am J Drug Alcohol Abuse 2019; 45:563-579.
- Kesner AJ, Lovinger DM. Cannabis use, abuse, and withdrawal: cannabinergic mechanisms, clinical, and preclinical findings. J Neurochem 2021; 157:1674-1696.
- Zehra A, Burns J, Liu CK, Manza P, Wiers CE, Volkow ND, Wang GJ. Cannabis addiction and the brain: a review. J Neuroimmune Pharmacol 2018; 13:438-452.
- Yücel M, Solowij N, Respondek C, et al. Regional brain abnormalities associated with long-term heavy cannabis use. Arch Gen Psychiatry 2008; 65:694-701.
