Castleman’s disease

Evidence-based neurology checklist on castleman’s disease: Pathology This is angiofollicular hyperplasia of lymph nodes It is a lymphoproliferative disorder Pathological types Haematological features Locations of extra-nodal masses Neurological features Types: Castleman’s disease without POEMS…

Pathology

  • This is angiofollicular hyperplasia of lymph nodes
  • It is a lymphoproliferative disorder

Pathological types

Haematological features

Locations of extra-nodal masses

Neurological features

Types: Castleman’s disease without POEMS syndrome (CD-PN)

Types: Castleman’s disease with POEMS syndrome (CD-POEMS)

Differential diagnosis of Castleman’s disease

Treatment

References

  1. Yu H, Yao F, Li Y, Li J, Cui QC. Castleman disease variant of POEMS syndrome complicated with multiple cerebral infarction: a rare case report and review of literature. Int J Clin Exp Pathol 2015; 8:13578-13583.
  2. Riccio A, Natale D, Pettinato G, Sparano L, Petto A, Puzziello A. Castleman's disease. Ann Rheum Dis 2001; 60:176.
  3. Smith C, Lee-Miller C, Dishop MK, Cost C, Wang M, Asturias EJ. Multicentric Castleman disease presenting with fever. J Pediatr 2014; 165:1261-1265. 
  4. Eward WC, DeWitt SB, Brigman BE, Kontogeorgakos V, Lagoo AS. Extranodal Castleman disease of the extremities: a case report and review of the literature. Skeletal Radiol 2014; 43:1627-1631. 
  5. Garcia T, Dafer R, Hocker S, Schneck M, Barton K, Biller J. Recurrent strokes in two patients with POEMS syndrome and Castleman's disease. J Stroke Cerebrovasc Dis 2007; 16:278-284.
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