White matter lesions (WML): regional differentials

Evidence-based neurology checklist on white matter lesions (wml): regional differentials: Frontal dominant Alexander disease Metachromatic leukodystrophy (MLD) Frontal variant Adrenoleukodystrophy (ALD) Parieto-occipital dominant Periventricular dominant Brainstem dominant Cerebellar dominant…

Frontal dominant

  • Alexander disease
  • Metachromatic leukodystrophy (MLD)
  • Frontal variant Adrenoleukodystrophy (ALD)

Parieto-occipital dominant

Periventricular dominant

Brainstem dominant

Cerebellar dominant

Subcortical dominant

Deep white matter

References

  1. Schiffmann R, van der Knaap MS. Invited article: an MRI-based approach to the diagnosis of white matter diseases. Neurology 2009; 72:750-759.
  2. Barkovich AJ. An approach to MRI of metabolic disorders in children. J Neuroradiol 2007; 34:75-88.

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