Warfarin: switching to new oral anticoagulants
Evidence-based neurology checklist on warfarin: switching to new oral anticoagulants: Indications to switch Difficulty instituting safe monitoring of international normalised ratio (INR) Inadequate time on therapeutic range (TTR) of INR Stroke developing whilst on adequate INR Patient preference…
Indications to switch
- Difficulty instituting safe monitoring of international normalised ratio (INR)
- Inadequate time on therapeutic range (TTR) of INR
- Stroke developing whilst on adequate INR
- Patient preference
- Concurrent use of Warfarin-interacting drugs
Process of switching
Switching to Warfarin from new anticoagulants
References
- Kirchhof P, Lip GYH, Van Gelder IC, et al. Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options- a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference. Europace 2012; 14:8-27.
- Agarwal MB, Verma S, Mahapatra M, et al. Balancing efficacy and bleeding risk in the prevention of stroke due to atrial fibrillation with newer oral anticoagulants. Indian J Hematol Blood Transfus 2012; 28:129-143.
- Weimer C, Hohnloser SH, Eikelboom JW, Diener H-C. Preventing cardioembolic stroke in atrial fibrillation with dabigatran. Curr Neurol Neurosci Rep 2012; 12:17-23.
