Warfarin: clinical use
Evidence-based neurology checklist on warfarin: clinical use: Characteristics Warfarin is a vitamin K antagonist It reduces stroke risk of non-valvular atrial fibrillation by 60% It achieves therapeutic INR only 60% of the time There is a 2% annual risk of major bleeding Contraindications Major…
Characteristics
- Warfarin is a vitamin K antagonist
- It reduces stroke risk of non-valvular atrial fibrillation by 60%
- It achieves therapeutic INR only 60% of the time
- There is a 2% annual risk of major bleeding
Contraindications
Major drug interactions
Causes of impaired response to Warfarin
Bridging therapy for Warfarin
Treatment of Warfarin-related bleeding
References
- Tendera M, Syzdol M, Parma Z. ARISTOTLE RE-LYs on the ROCKET. What's new in stroke prevention in patients with atrial fibrillation? Cardiol J 2012; 19:4-10.
- Vahedi K, Amarenco P. Cardiac causes of stroke. Curr Treat Options Neurol 2000; 2:305-317.
- Larson ST, Ray BE, Wilbur J. Ischemic stroke management: posthospitalization and transition of care. Am Fam Physician 2023; 108:70-77.
- Eckman MH, Rosand J, Knudsen KA, Singer DE, Greenberg SM. Can patients be anticoagulated after intracerebral hemorrhage: a decision analysis. Stroke 2003; 34:1710-1716.
- Goldstein JN, Greenberg SM. Should anticoagulation be resumed after intracerebral hemorrhage? Cleve Clin J Med 2010; 77:791-799.
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