Vitamin B12 deficiency: causes and risk factors

Evidence-based neurology checklist on vitamin b12 deficiency: causes and risk factors: Gastrointestinal disorders Pernicious anaemia Coeliac disease Malabsorption Achlorhydria Gastrointestinal disorders Gastric or intestinal surgery Gastritis Helicobacter pylori Gastric atrophy Intestinal…

Gastrointestinal disorders

  • Pernicious anaemia
  • Coeliac disease
  • Malabsorption
  • Achlorhydria
  • Gastrointestinal disorders
  • Gastric or intestinal surgery
  • Gastritis
  • Helicobacter pylori
  • Gastric atrophy
  • Intestinal bacterial overgrowth of the intestine

Drug-induced

Dietary factors

Other risk factors

References

  1. Reynolds E. Vitamin B12, folic acid and the nervous system. Lancet Neurol 2006; 5:949-960.
  2. Reinstatler L, Qi YP, Williamson RS, Garn JP, Oakley GP. Association of biochemical B12 deficiency with metformin therapy and vitamin B12 supplements. Diabetes Care 2012; 35:327-333.
  3. Probasco JC, Felling RJ, Carson JT, Dorsey ER, Niessen TM. Teaching Neuroimage: Myelopathy due to B12 deficiency in long-term colchicine treatment and nitrous oxide misuse. Neurology 2011; 77:e51.
  4. Hvas AM, Nexo E. Diagnosis and treatment of vitamin B12 deficiency-an update. Haematologica 2006; 91:1506-1512.
  5. Herrmann W, Obeid R. Causes and early diagnosis of vitamin B12 deficiency. Dtsch Arztebl Int 2008; 105:680-685.
  6. And 2 more. Subscribe to see the full list

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