Valproate: side effects

Evidence-based neurology checklist on valproate: side effects: Foetal valproate spectrum disorder (FVSD) See Neurochecklist: “Foetal valproate spectrum disorder” Hyperammonemia Movement disorders Other neurological side effects Systemic side effects Neurodevelopmental disorders with paternal…

Foetal valproate spectrum disorder (FVSD)

  • See Neurochecklist: “Foetal valproate spectrum disorder”

Hyperammonemia

Movement disorders

Other neurological side effects

Systemic side effects

Neurodevelopmental disorders with paternal valproate use

References

  1. Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415. 
  2. Lind J, Nordlund P. Intravenous use of valproic acid in status epilepticus is associated with high risk of hyperammonemia. Seizure 2019; 69:20-24.
  3. Panda S, Radhakrishnan K. Two cases of valproate-induced hyperammonemic encephalopathy without hepatic failure. J Assoc Physicians India 2004; 52:746-748.
  4. Chopra A, Kolla BP, Mansukhani MP, Netzel P, Frye MA. Valproate-induced hyperammonemic encephalopathy: an update on risk factors, clinical correlates and management. Gen Hosp Psychiatry 2012; 34:290-298.
  5. Wadzinski J, Franks R, Roane D, Bayard M. Valproate-associated hyperammonemic encephalopathy. J Am Board Fam Med 2007; 20:499-502.
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