Tumefactive multiple sclerosis (TMS): clinical features

Evidence-based neurology checklist on tumefactive multiple sclerosis (tms): clinical features: Demographic features This accounts for about 1-3 per 1000 cases of MS It especially occurs in the third to fourth decades of life The affected patients are young and are more likely to be female Possible…

Demographic features

  • This accounts for about 1-3 per 1000 cases of MS
  • It especially occurs in the third to fourth decades of life
  • The affected patients are young and are more likely to be female

Possible triggers

Clinical features

Outcome

Poor prognostic features

Acronym

References

  1. Algahtani H, Shirah B, Alassiri A. Tumefactive demyelinating lesions: a comprehensive review. Mult Scler Relat Disord 2017; 14:72-79. 
  2. Lucchinetti CF, Gavrilova RH, Metz I, et al. Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis. Brain 2008; 131:1759-1775. 
  3. Hardy TA, Chataway J. Tumefactive demyelination: an approach to diagnosis and management. JNNP 2013; 84:1047-1053. 
  4. Pilz G, Harrer A, Wipfler P, et al. Tumefactive MS lesions under fingolimod: a case report and literature review. Neurology 2013; 81:1654-1658. 
  5. Visser F, Wattjes MP, Pouwels PJ, Linssen WH, van Oosten BW. Tumefactive multiple sclerosis lesions under fingolimod treatment. Neurology 2012; 79:2000-2003.
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