Tumefactive demyelination (TD): causes

Evidence-based neurology checklist on tumefactive demyelination (td): causes: Definition Demyelinating lesions ≥2 cm or Demyelinating lesions between 0.5-2 cm with mass effect Inflammatory Neoplastic Vascular Infectious Paraneoplastic: antibodies Acronym

Definition

  • Demyelinating lesions ≥2 cm or
  • Demyelinating lesions between 0.5-2 cm with mass effect

Inflammatory

Neoplastic

Vascular

Infectious

Paraneoplastic: antibodies

Acronym

References

  1. Algahtani H, Shirah B, Alassiri A. Tumefactive demyelinating lesions: a comprehensive review. Mult Scler Relat Disord 2017; 14:72-79. 
  2. Lucchinetti CF, Gavrilova RH, Metz I, et al. Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis. Brain 2008; 131:1759-1775. 
  3. Hardy TA, Chataway J. Tumefactive demyelination: an approach to diagnosis and management. JNNP 2013; 84:1047-1053.
  4. Nakayama M, Naganawa S, Ouyang M, Jones KA, Kim J, Capizzano AA, Moritani T. A review of clinical and imaging findings in tumefactive demyelination. Am J Roentgenol 2021; 217:186-197.
  5. Lin X, Yu W-Y, Liauw L, et al. Clinicoradiologic features distinguish tumefactive multiple sclerosis from CNS neoplasms. Neurol Clin Pract 2017; 7:53-64. 
  6. And 8 more. Subscribe to see the full list

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