Tardive dystonia: clinical features

Evidence-based neurology checklist on tardive dystonia: clinical features: Demographic features The mean age at onset is about 38 years It sets in about 6 years after starting treatment: the range is 4 days to 23 years Men are younger than women at onset A shorter exposure period is required in…

Demographic features

  • The mean age at onset is about 38 years
  • It sets in about 6 years after starting treatment: the range is 4 days to 23 years
  • Men are younger than women at onset
  • A shorter exposure period is required in men
  • It is focal onset in >80% of cases
  • It remains focal in only 17% of severe cases
  • Remission occurs in about 15%: this is after a mean of about 5 years

Clinical features

Aggravating factors

Relieving factors

Differential diagnosis

References

  1. Kiriakakis V, Bhatia KP, Quinn NP, Marsden CD. The natural history of tardive dystonia. A long-term follow-up study of 107 cases. Brain 1998; 121:2053-2066.
  2. Suzuki T, Matsuzaka H. Drug-induced Pisa syndrome (pleurothotonus): epidemiology and management. CNS Drugs 2002; 16:165-174.
  3. Bhattacharjee S, Tiwari M, Dutt A, Kumar H. Olanzapine-induced task specific tardive dystonia and its response to carbamazepine: a case report. Neurol India 2012; 60:649-650. 
  4. van Harten PN, Kahn RS. Tardive dystonia. Schizophr Bull 1999; 25:741-748.

Related checklists

Loading...