Stiff person syndrome (SPS): investigational treatments
Evidence-based neurology checklist on stiff person syndrome (sps): investigational treatments: Anti B cell agents Ocrelizumab Ofatumumab Inebilizumab Ublituximab Obexelimab Obinutuzumab Obinutuzumab Bortezomib Daratumumab FcRn inhibitors Bruton kinase inhibitors Anti IL6 receptor antagonists
Anti B cell agents
- Ocrelizumab
- Ofatumumab
- Inebilizumab
- Ublituximab
- Obexelimab
- Obinutuzumab
- Obinutuzumab
- Bortezomib
- Daratumumab
FcRn inhibitors
Bruton kinase inhibitors
Anti IL6 receptor antagonists
References
- Dalakas MC. Therapies in stiff-person syndrome: advances and future prospects based on disease pathophysiology. Neurol Neuroimmunol Neuroinflamm 2023; 10:e200109.
- Di Stefano V, Alonge P, Rini N, Militello M, Lupica A, Torrente A, Brighina F. Efgartigimod beyond myasthenia gravis: the role of FcRn-targeting therapies in stiff-person syndrome. J Neurol 2024; 271:254-262.
