Statin myopathy: investigations
Evidence-based neurology checklist on statin myopathy: investigations: Routine investigations Creatinine kinase (CK) Thyroid stimulating hormone (TSH): hypothyroidism causes raised CK and lipids Liver enzymes Vitamin D Erythrocyte sedimentation rate (ESR) Anti HMGCoAR antibodies Investigations if…
Routine investigations
- Creatinine kinase (CK)
- Thyroid stimulating hormone (TSH): hypothyroidism causes raised CK and lipids
- Liver enzymes
- Vitamin D
- Erythrocyte sedimentation rate (ESR)
- Anti HMGCoAR antibodies
Investigations if CK is >10 times normal
Investigations if associated with metabolic features
Investigations if associated with unusual features
Investigations if symptoms progress after stopping statins
References
- Sathasivam S, Lecky B. Statin induced myopathy. BMJ 2008; 337:a2286.
- Baker SK, Tarnopolsky MA. Statin myopathies: pathophysiologic and clinical perspectives. Clin Invest Med 2001; 24:258-272.
- Radcliffe KA, Campbell WW. Statin myopathy. Curr Neurol Neurosci Rep 2008; 8:66-72.
- Fernandez G, Spatz ES, Jablecki C, Phillips PS. Statin myopathy: a common dilemma not reflected in clinical trials. Cleve Clinic J Med 2011; 78:393-503.
- Siddiqi SA, Thompson PD. How do you treat patients with myalgia who take statins? Curr Atheroscler Rep 2009; 11:9-14.
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