Spontaneous intracranial hypotension (SIH): clinical features

Evidence-based neurology checklist on spontaneous intracranial hypotension (sih): clinical features: Epidemiology Females are more frequently affected The peak incidence age is 40 years It could be familial There is a mechanical cause in a third of cases Types of spinal CSF leaks Typical headache…

Epidemiology

  • Females are more frequently affected
  • The peak incidence age is 40 years
  • It could be familial
  • There is a mechanical cause in a third of cases

Types of spinal CSF leaks

Typical headache features

Atypical headache features

Auditory features

Movement disorders

Other associated features

Unusual presentations

References

  1. Schievink WI. Spontaneous spinal cerebrospinal fluid leaks and intracranial hypotension. JAMA 2006; 295:2286-2296. 
  2. Leep Hunderfund AN, Mokri B. Orthostatic headache without CSF leak. Neurology 2008; 71:1902-1906.
  3. Schievink WI, Maya MM, Jean-Pierre S, Nuño M, Prasad RS, Moser FG. A classification system of spontaneous spinal CSF leaks. Neurology 2016; 87:673-679. 
  4. Mokri B. Familial occurrence of spontaneous spinal CSF leaks: underlying connective tissue disorder. Headache 2008; 48:146-163.
  5. Shah VN, Dillon WP. Spontaneous intracranial hypotension with brain sagging attributable to a cerebrospinal fluid-venous fistula. JAMA Neurol 2020 (Online ahead of print).
  6. And 15 more. Subscribe to see the full list

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