Frontotemporal brain sagging syndrome (FBSS)

Evidence-based neurology checklist on frontotemporal brain sagging syndrome (fbss): Pathology This is brain sagging secondary to intracranial hypotension It may be spontaneous It may follow dural puncture It may also result from cerebrospinal fluid-venous fistula (CSF-venous fistula) Epidemiology…

Pathology

  • This is brain sagging secondary to intracranial hypotension
  • It may be spontaneous
  • It may follow dural puncture
  • It may also result from cerebrospinal fluid-venous fistula (CSF-venous fistula)

Epidemiology

Behavioural features

Bulbar features

Other features

Differential diagnosis

Magnetic resonance imaging (MRI) brain: features

Cerebrospinal fluid (CSF) analysis

Electroencephalogram (EEG)

Positron emission tomography (PET) scan

Treatment

Synonym

References

  1. Wicklund MR, Mokri B, Drubach DA, Boeve BF, Parisi JE, Josephs KA. Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD. Neurology 2011; 76:1377-1382.
  2. Slattery CF, Malone IB, Clegg SL, Warren JD, Fox NC. Reversible frontotemporal brain sagging syndrome. Neurology 2015; 85:833.
  3. Schievink WI, Maya M, Barnard Z, et al. The reversible impairment of behavioral variant frontotemporal brain sagging syndrome: Challenges and opportunities. Alzheimers Dement (N Y) 2022; 8:e12367.
  4. Ortega-Porcayo LA, Ortega EP, Quiroz-Castro O, et al. Frontotemporal brain sagging syndrome: craniospinal hypovolemia secondary to a T6-T7 cerebrospinal fluid-venous fistula. Surg Neurol Int 2020; 11:250.
  5. Lashkarivand A, Eide PK. Brain sagging dementia-diagnosis, treatment, and outcome: a review. Neurology 2022; 98:798-805.
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