Small fiber neuropathy: clinical features

Evidence-based neurology checklist on small fiber neuropathy: clinical features: Neuropathy pattern There is a trigger event in 80% of acute onset cases (AOSFN) It is typically non-length dependent Neuropathic pain: features Sensory symptoms Autonomic symptoms Other symptoms Water immersion…

Neuropathy pattern

  • There is a trigger event in 80% of acute onset cases (AOSFN)
  • It is typically non-length dependent

Neuropathic pain: features

Sensory symptoms

Autonomic symptoms

Other symptoms

Water immersion wrinkling test

Progress and outcome

References

  1. Devigili G, Tugnoli V, Penza P, et al. The diagnostic criteria for small fiber neuropathy: from symptoms to neuropathology. Brain 2008; 131:1912-1925.
  2. Tavee J, Zhou L. Small fiber neuropathy: a burning problem. Cleve Clin J Med 2009; 76:297-305.
  3. Terkelsen AJ, Karlsson P, Lauria G, Freeman R, Finnerup NB, Jensen TS. The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes. Lancet Neurol 2017; 16:934-944.
  4. Gendre T, Lefaucheur J-P, Nordine T, et al. Characterizing acute-onset small fiber neuropathy. Neurol Neuroimmunol Neuroinflamm 2024; 11:e200195.
  5. Scadding J. Neuropathic pain. ACNR 2003; 3:8-14.
  6. And 1 more. Subscribe to see the full list

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