Sleeping sickness: pathology

Evidence-based neurology checklist on sleeping sickness: pathology: Trypanosoma brucei gambiense This is the West African form It is transmitted by the tsetse fly Glossina palpalis Humans are the main reservoirs It accounts for 97% of human infections It causes chronic infection lasting about…

Trypanosoma brucei gambiense

  • This is the West African form
  • It is transmitted by the tsetse fly Glossina palpalis
  • Humans are the main reservoirs
  • It accounts for 97% of human infections
  • It causes chronic infection lasting about three years

Trypanosoma brucei rhodesiense

Transmission

Routes of entry into the central nervous system

Pathology

Synonyms

References

  1. Dzikowiec M, Góralska K, Błaszkowska J. Neuroinvasions caused by parasites. Ann Parasitol 2017; 63:243–253.
  2. Malvy D, Chappuis F. Sleeping sickness. Clin Microbiol Infect 2011; 17:986-995. 
  3. Ehrhardt S, Lippert U, Burchard GD, Sudeck H. Orchitis as an unusual manifestation of human African trypanosomiasis. J Infect 2006; 52:e31-e33. 
  4. Kennedy PG. Human African trypanosomiasis of the CNS: current issues and challenges. J Clin Invest 2004; 113:496-504. 

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