Schizophrenia: treatment

Evidence-based neurology checklist on schizophrenia: treatment: Second generation antipsychotics Clozapine: this is the most effective Olanzapine Risperidone Quetiapine Paliperidone Ziprasidone Molindone Third generation antipsychotics First generation antipsychotics: rarely used Non-drug treatments

Second generation antipsychotics

  • Clozapine: this is the most effective
  • Olanzapine
  • Risperidone
  • Quetiapine
  • Paliperidone
  • Ziprasidone
  • Molindone 

Third generation antipsychotics

First generation antipsychotics: rarely used

Non-drug treatments

References

  1. Picchioni MM, Murray RM. Schizophrenia. BMJ 2007; 335:91-95. 
  2. Stępnicki P, Kondej M, Kaczor AA. Current concepts and treatments of schizophrenia. Molecules 2018; 23:2087.
  3. Faden J, Citrome L. Resistance is not futile: treatment-refractory schizophrenia - overview, evaluation and treatment. Expert Opin Pharmacother 2019; 20:11-24.
  4. Xu F, Xu S. Cognitive-behavioral therapy for negative symptoms of schizophrenia: A systematic review and meta-analysis. Medicine (Baltimore) 2024; 103:e39572.

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