REM sleep behaviour disorder (RBD): management

Evidence-based neurology checklist on rem sleep behaviour disorder (rbd): management: Main recommended drug treatments Clonazepam <2mg nocte Melatonin 3–12 mg taken 30 minutes before sleep Drug treatments which may also worsen RBD Poorly evidenced drug treatments Environmental treatments…

Main recommended drug treatments

  • Clonazepam <2mg nocte
  • Melatonin 3–12 mg taken 30 minutes before sleep

Drug treatments which may also worsen RBD

Poorly evidenced drug treatments

Environmental treatments

Pressurised bed alarm

References

  1. Aurora RN, Zak RS, Maganti RK, et al. Best practice guide for the treatment of REM sleep behaviour disorder (RBD). J Clin Sleep Med 2010; 15:85-95.
  2. Thomas A, Bonanni L, Onofrj M. Symptomatic REM sleep behaviour disorder. Neurol Sci 2007; 28:S21-S36.
  3. Wilson SJ, Nutt DJ, Argyropoulos SV, et al. British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J Psychopharmacol 2010; 24:1577-1600.
  4. Iranzo A, Santamaria J, Tolosa E. Idiopathic rapid eye movement sleep behaviour disorder: diagnosis, management, and the need for neuroprotective interventions. Lancet Neurol 2016; 15:405-419. 
  5. Boeve BF. REM sleep behaviour disorder: updated review of the cite features, the RBD-neurodegenerative disease association, evolving concepts, controversies, and future directions. Ann N Y Acad Sci 2010; 1184:15-54.
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