Refractory myasthenia gravis (MG): clinical features

Evidence-based neurology checklist on refractory myasthenia gravis (mg): clinical features: Definition This is inadequate response to conventional MG treatment for ≥12 months It also describes disease relapse when immunosuppressive drug doses are reduced It develops in 10% of people with MG Risk…

Definition

  • This is inadequate response to conventional MG treatment for ≥12 months
  • It also describes disease relapse when immunosuppressive drug doses are reduced
  • It develops in 10% of people with MG

Risk factors

Risk medical factors

Course

References

  1. Sudulagunta SR, Sepehrar M, Sodalagunta MB, et al. Refractory myasthenia gravis-clinical profile, comorbidities and response to rituximab. Ger Med Sci 2016; 14:Doc12. 
  2. Suh J, Goldstein JM, Nowak RJ. Clinical characteristics of refractory myasthenia gravis patients. Yale J Biol Med 2013; 86:255-260. 
  3. Mantegazza R, Antozzi C. When myasthenia gravis is deemed refractory: clinical signposts and treatment strategies. Ther Adv Neurol Disord 2018; 11:1756285617749134.
  4. Sudulagunta SR, Sepehrar M, Sodalagunta MB, et al. Refractory myasthenia gravis - clinical profile, comorbidities and response to rituximab. Ger Med Sci 2016; 14:Doc12.

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