Refractory epilepsy: interventional treatments

Evidence-based neurology checklist on refractory epilepsy: interventional treatments: Deep brain stimulation (DBS): targets The anterior nucleus of the thalamus: this is the only FDA-approved target The hippocampus The centromedian nucleus Deep brain stimulation (DBS): benefits Other forms of…

Deep brain stimulation (DBS): targets

  • The anterior nucleus of the thalamus: this is the only FDA-approved target
  • The hippocampus
  • The centromedian nucleus

Deep brain stimulation (DBS): benefits

Other forms of neurostimulation

Epilepsy surgery

Other interventions

Synonyms

References

  1. Beleza P. Refractory epilepsy: a clinically oriented review. Eur Neurol 2009; 62: 65-71.
  2. Krauss GL, Sperling MR. Treating patients with medically resistant epilepsy. Neurol Clin Pract 2011; 1: 14-22.
  3. Yassin A, Al-Kraimeen L, Qarqash A, et al. Deep brain stimulation targets in drug-resistant epilepsy: Systematic review and meta-analysis of effectiveness and predictors of response. Seizure 2024; 122:144-152.
  4. Li MCH, Cook MJ. Deep brain stimulation for drug-resistant epilepsy. Epilepsia. 2018; 59:273-290. 
  5. Chang B, Xu J. Deep brain stimulation for refractory temporal lobe epilepsy: a systematic review and meta-analysis with an emphasis on alleviation of seizure frequency outcome. Childs Nerv Syst 2018; 34:321-327.
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