Progressive supranuclear palsy (PSP): variants and subtypes

Evidence-based neurology checklist on progressive supranuclear palsy (psp): variants and subtypes: Classic Richardson syndrome Early falls are characteristic PSP-Parkinsonism PSP-progressive gait freezing (PGF) Early onset PSP (EOPSP) Other variants PSP Subtypes

Classic Richardson syndrome

  • Early falls are characteristic

PSP-Parkinsonism

PSP-progressive gait freezing (PGF)

Early onset PSP (EOPSP)

Other variants

PSP Subtypes

References

  1. Williams DR, Lees AJ. Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges. Lancet Neurol 2009; 8:270-279.
  2. Williams DR, de Silva R, Paviour DC, et al. Characteristics of two distinct phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism. Brain 2005; 128:1247-1258.
  3. Rowe JB, Holland N, Rittman T. Progressive supranuclear palsy: diagnosis and management. Pract Neurol 2021 (online ahead of print).
  4. Jabbari E, Woodside J, Tan MMX, et al. The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy. Mov Disord 2019; 34:1307-1314. 
  5. Rohrer JD, Paviour D, Bronstein AM, O'Sullivan SS, Lees A, Warren JD. Progressive supranuclear palsy syndrome presenting as progressive nonfluent aphasia: a neuropsychological and neuroimaging analysis. Mov Disord 2010; 25:179-188.
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